Thanks to all WPMU for your support and help

In conjunction with our partners WPMU we have put together 2 website packages to help Ryan McLaughlin save the shine on Scotland campaign and the shine on ms social network from impending closure. These exclusive website packages can only be purchased for a limited time via the shine on Scotland campaign website.

Despite Ryan having a hectic schedule carrying the olympic flame in the torch relay a few weeks ago he also has school, helps care for his mum and runs the campaign.

Ryan has kindly given a lot of his valued personal time to help develop this platform for the good of other causes and charities and we are glad to give him a helping hand in his campaign to save his mum. On behalf of the team at causeblogs and WPMU we thank Ryan for the time and commitment he has put into helping others and wish all the very best.

If for some reason you havent seen the campaign please watch the video below – A Inspirational Cause !

To help us save the campaign and our network from impending closure our friends at WPMUand have put together some really amazing website packages aiming to helping Ryan raise urgent funds needed to continue. We have been given Ryan the following Exclusive web packages to sell at a massive discounted rate. would like to thank our partners WPMU and Psek Hosting for helping put these packages together to help Ryan fight on !

  • shineadmin

    HI Arun - Breaking news worldwide

    MS breakthrough: Vitamin D directly terminates production of disease-causing protein.

    Posted by Alan on Wednesday, August 17th 2011 edit

    Mechanism suggests a potential new path toward pharmaceutical treatment of MS, as well as therapies for other autoimmune diseases such as rheumatoid arthritis, type 1 diabetes, eczema and psoriasis.

    For years scientists have noted an association between levels of vitamin D in a person’s body and the person’s ability to resist or minimize the effects of multiple sclerosis (MS) but didn’t understood the mechanism involved. Until now.

    New breakthrough research by a collaborative team at UMDNJ-New Jersey Medical School and Stanford indicates that vitamin D directly terminates the production of a disease-causing protein.

    As the investigators outline in their report, published in the September issue of Molecular and Cellular Biology (“1,25-Dihydroxyvitamin D3 ameliorates Th17 autoimmunity via transcriptional modulation of interleukin-17A” ):

    • During MS (“EAE” in mice), a damaging protein called interleukin-17 (IL-17) is produced by immune cells in the brain.

    • The research team found that after vitamin D binds to its receptor, the receptor parks itself on the gene that encodes IL-17.

    • By doing so, the vitamin D receptor occupies a site normally reserved for a protein called NFAT, which is required to turn the IL-17 gene on.

    • The gene stays off and IL-17 levels plummet.

    • At the same time, the vitamin D receptor turns on another gene, whose product generates suppressive T cells that combat the destructive action of their IL-17-producing counterparts.

    According to the researchers, led by UMDNJ Prof. Sylvia Christakos, PhD, the mechanism they identified suggests what might be a new path toward pharmaceutical treatment of MS, as well as therapies for other autoimmune diseases that might include rheumatoid arthritis, type 1 diabetes, eczema and psoriasis.

    Source: ProHealth Copyright © 2011 ProHealth, Inc. (17/08/11)

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