Warning: Creating default object from empty value in /usr/web/www.site.edu/wp-includes/ms-settings.p

Every time a new site is created on our WPMU we get this error message when clicking on the activation link.

Warning: Creating default object from empty value in /usr/web/www.site.edu/wp-includes/ms-settings.php on line 111

This seems like part of a bigger underlying problem does anyone know what this could be all about?