What is the Best php config for WP ?

I get a lot of "problem", nginx time-out, long time and so and I would like to know what is the config to choose. Im using Plesk 12 and apache, nginx, php and cent os.
The choice are in my actual server config :
1. PHP 5.4.16 by os vendor
a. FastCGI by Apache
b. PHP by Apache
c. PHP by nginx
2. PHP 5.6.19
a. FastCGI by Apache
b. PHP by Apache
c. PHP by nginx
3. PHP 7.0.6
a. FastCGI by Apache
b. PHP by Apache
c. PHP by nginx
What is the choice to get the best config with buddy press multisite ?
Thank you