when using e-newsletter plugin in multisite, do I send from network admin or root site?

(not getting installed plugin menu. might be my internet connection. setting to ‘advanced wordpress’ question instead)

anyway, basically in the title. i’ve gotten the e-newsletter plugin. is it better form to send the newsletter from my network admin dashboard? (at least for newsletters from the main site, ‘intothemythica.com’.

i understand that i can use the newsletter with different sites within my network, just wondering about the main site.