I just upgraded the lavawine.org site to WordPress 4.5 as recommended by WordPress. When I did this, I got a 500 server error. Was able to get into it and disable all plugins. The site came back up. Then, one by one, I re-enabled each plugin. Every time I activated Events+ the site crashed - was not able to display anything.
I have activated WPMU support access for you to look into this.
Please advise ASAP as we have events coming up next week that people need to know about.